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No Milan travel guide would be complete without the Quadrilatero della Moda. Via Montenapoleone, Via della Spiga, Via Sant'Andrea, and Via Manzoni form a grid of streets housing the world's most prestigious fashion houses: Gucci, Prada, Versace, Armani, Dolce & Gabbana, and more. Milan Fashion Week occurs twice annually (February and September) - the city transforms entirely during these weeks.
Pro Tip: Even if high fashion isn't your thing, Via della Spiga is the most architecturally beautiful street in Milan - a pedestrianised lane of elegant facades and hidden courtyards worth walking for the architecture alone.